Relevant publications

  1. Novak R, Jacob E, Haimovich J, Avni O, Melamed D. The MAPK/ERK and PI(3)K Pathways Additively Coordinate the Transcription of Recombination-Activating Genes in B Lineage Cells. (2010). Immunol. 185:3239-3247.
  2. Keren Z., Naor S., Nussbaum S. Golan K. Itkin T. Sasaki Y., Schmidt-Supprian M., Lapidot T. and Melamed D. B cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging. (2011) Blood. 117: 3104-3112. See also commentary on this article in Blood 2011, 117:2985.
  3. Keren Z, Averbuch D, Shahaf G, Zisman-Rozen S, Golan K, Itkin T, Lapidot T, Mehr R and Melamed D. Chronic B cell deficiency from birth prevents age-related alterations in the B lineage.(2011) Immunol. 187: 2140-2147.
  4. Melamed D and Scott DW. (2012). Aging and neoteny in the B lineage. 120: 4143 – 4149.
  5. Kessel A, Haj T, Peri R, Snir A, Melamed D, Sabo E, Toubi E. Human CD19(+)CD25(high) B regulatory cells suppress proliferation of CD4(+) T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells. (2012) Autoimmun Rev. 11: 670-677.
  6. Diamant E. and Melamed D. (2013). B Cell Central Tolerance: Controlling Self-Reactive B Cells in the Bone Marrow. Encyclopedia of Medical Immunology-Autoimmune Diseases. Springer Science+Buisness. 155-160.
  7. Melamed D. (2013). Homeostatic regulation of aging and rejuvenation in the B lineage. Rev.Immunol. 33: 41-56.